{"id":858,"date":"2021-06-01T18:48:30","date_gmt":"2021-06-01T09:48:30","guid":{"rendered":"http:\/\/doujitsu.dept.med.gunma-u.ac.jp\/cms\/?p=858"},"modified":"2022-04-15T19:07:35","modified_gmt":"2022-04-15T10:07:35","slug":"%e4%bd%90%e3%80%85%e6%9c%a8%e5%8a%a9%e6%95%99%e3%81%8c%e7%ad%86%e9%a0%ad%e8%91%97%e8%80%85%e3%81%ae%e8%ab%96%e6%96%87%e3%81%8cjournal-of-reproduction-and-development%e3%81%ab%e6%8e%b2%e8%bc%89","status":"publish","type":"post","link":"http:\/\/doujitsu.dept.med.gunma-u.ac.jp\/cms\/?p=858","title":{"rendered":"\u4f50\u3005\u6728\u52a9\u6559\u306e\u539f\u8457\u8ad6\u6587\u304cJournal of Reproduction and Development\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f"},"content":{"rendered":"<p>\u4f50\u3005\u6728\u52a9\u6559\u304c\u7b46\u982d\u8457\u8005\u3068\u306a\u3063\u305f\u539f\u8457\u8ad6\u6587\u304cJournal of Reproduction and Development\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<p>&#8220;Oocyte-Specific gene knockdown by intronic artificial microRNAs driven by Zp3 transcription in mice&#8221;<br \/>\nKeisuke Sasaki, Saaya Takaoka, Yayoi Obata.<br \/>\nJ Reprod Dev. 2021 Jun; 67(3):229\u2013234.<br \/>\nDOI: <a href=\"https:\/\/doi.org\/10.1262\/jrd.2020-146\">https:\/\/doi.org\/10.1262\/jrd.2020-146<\/a> (J-Stage)<\/p>\n<p>\uff08\u6982\u8981\uff09<br \/>\nCRISPR-Cas9\u3092\u7528\u3044\u305f\u30b2\u30ce\u30e0\u7de8\u96c6\u306b\u3088\u308a\u3001Cre\/loxP\u306b\u4f9d\u5b58\u3057\u306a\u3044\u65b0\u898f\u306e\u5375\u7279\u7570\u7684\u306a\u907a\u4f1d\u5b50\u6a5f\u80fd\u963b\u5bb3\u6cd5\u3092\u958b\u767a\u3057\u307e\u3057\u305f\u3002\u4eba\u5de5\u7684\u306b\u8a2d\u8a08\u3055\u308c\u305fmicroRNA\u3092\u5375\u7279\u7570\u7684\u306b\u767a\u73fe\u3059\u308b\u907a\u4f1d\u5b50\u306e\u30a4\u30f3\u30c8\u30ed\u30f3\u306b\u30ce\u30c3\u30af\u30a4\u30f3\u3059\u308b\u3053\u3068\u3067\u3001\u4f5c\u51fa\u3057\u305f\u907a\u4f1d\u5b50\u6539\u5909\u30de\u30a6\u30b9\u3067\u306f\u5375\u7279\u7570\u7684\u306a\u907a\u4f1d\u5b50\u767a\u73fe\u3092\u963b\u5bb3\u304c\u8d77\u3053\u308a\u307e\u3059\u3002\u4eca\u5f8c\u3001\u5375\u4ee5\u5916\u306b\u3082\u69d8\u3005\u306a\u7d30\u80de\u30fb\u7d44\u7e54\u3078\u306e\u5fdc\u7528\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4f50\u3005\u6728\u52a9\u6559\u304c\u7b46\u982d\u8457\u8005\u3068\u306a\u3063\u305f\u539f\u8457\u8ad6\u6587\u304cJournal of Reproduction and Development\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002 &#8220;Oocyte-Specific gene knockdown by i [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[5,3],"tags":[],"_links":{"self":[{"href":"http:\/\/doujitsu.dept.med.gunma-u.ac.jp\/cms\/index.php?rest_route=\/wp\/v2\/posts\/858"}],"collection":[{"href":"http:\/\/doujitsu.dept.med.gunma-u.ac.jp\/cms\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/doujitsu.dept.med.gunma-u.ac.jp\/cms\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/doujitsu.dept.med.gunma-u.ac.jp\/cms\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/doujitsu.dept.med.gunma-u.ac.jp\/cms\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=858"}],"version-history":[{"count":5,"href":"http:\/\/doujitsu.dept.med.gunma-u.ac.jp\/cms\/index.php?rest_route=\/wp\/v2\/posts\/858\/revisions"}],"predecessor-version":[{"id":866,"href":"http:\/\/doujitsu.dept.med.gunma-u.ac.jp\/cms\/index.php?rest_route=\/wp\/v2\/posts\/858\/revisions\/866"}],"wp:attachment":[{"href":"http:\/\/doujitsu.dept.med.gunma-u.ac.jp\/cms\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=858"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/doujitsu.dept.med.gunma-u.ac.jp\/cms\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=858"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/doujitsu.dept.med.gunma-u.ac.jp\/cms\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=858"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}